Research & News
Bookmark and Share

Misconceptions About the Causes of Cancer

Type: Books
Date Published: February 20, 2003
Authors:
Research Topics:
Environment, Health, Risk & Regulation
The major avoidable causes of cancer are: (1) smoking, which accounts for 27% of cancer deaths in Canada and 80% to 90% of deaths from lung cancer; (2) dietary imbalances (e.g., lack of sufficient amounts of dietary fruits and vegetables), which account for about an­other third; (3) chronic infections, mostly in developing countries; and (4) hormonal factors, which are influenced primarily by life-style.

There is no cancer epidemic except for lung cancer due to smoking. (Cancer is actually many diseases, and the causes differ for cancers at different target sites.) Since 1971, over­all can­cer mortality rates in Canada (exclud­ing lung can­cer) have declined 17% in women and 5% in men. Regulatory policy that focuses on traces of synthetic chemicals is based on miscon­ceptions about animal cancer tests. Current research indicates that it is not rare for substances to cause cancer in laboratory rodents in the standard high-dose experiments. Half of all chemicals tested, whether occur­ring naturally or pro­duced synthetically, are "carcinogens"; there are high-dose effects in rodent cancer tests that are not relevant to low-dose human exposures and which may contribute to the high proportion of chemicals that test positive.

The focus of regulatory policy is on synthetic chemi­cals, but 99.9% of the chemicals humans ingest are natural. For example, more than 1000 naturally occurring chemicals have been de­scribed in coffee: 30 have been tested and 21 have been found to be carcinogenic in rodents in high-dose tests. Plants in the human diet contain thousands of natural "pesticides" produced by plants to protect themselves from in­sects and other predators: 72 have been tested and 38 have been found to give cancer to rodents. Thus, exposure to synthetic rodent carcinogens is small compared to the natural background of rodent carcinogens. High-dose rodent cancer tests need to be re-evaluated by viewing results from this perspective.

There is no convincing evidence that synthetic chemical pollutants are important as a cause of human cancer. Regulations targeted to eliminate low levels of synthetic chemi­cals are enor­mously expensive: the United States Environmental Protection Agency (EPA) has estimated that envi­ron­mental regulations cost $140 billion per year in the United States. Others have estimated that the me­dian toxic control program costs 146 times more per hypothetical life-year saved than the me­dian medical in­tervention. Attempting to reduce low hypothetical risks has other costs as well: if re­ducing syn­thetic pesticides makes fruits and vegetables more expensive, thereby decreasing consumption, then the cancer rate will likely increase. The prevention of cancer will come from knowledge obtained from biomedical research, education of the public, and life-style changes made by individuals. A re-examination of priorities in cancer prevention, both public and pri­vate, seems called for.

In this study, we highlight nine misconceptions about pollution, pesticides, and the causes of cancer. We briefly present the scientific evidence that undermines each misconception. The nine misconceptions are listed in Contents (p. v-vi) and an extensive bibliography is pro­vided in References and further reading (p. 99). Phrases in the text typeset like this, carcinogenic potency, are defined in the Glossary (p. 91).
Free Download(s):
[Buy print version : Add to shopping cart]


Loading...